HitPredict

Interactor 1: H2B2 (P02294)
Histone H2B.2
Gene: HTB2

Interactor 2: ORC1 (P54784)
Origin recognition complex subunit 1 (Origin recognition complex 120 kDa subunit)
Gene: ORC1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	16554755, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 914
+	Sc
		355584 H2B1_YEAST (1-131): 4.04e-44: 142: 96.95		ORC1_YEAST (1-914): 0: 798: 100.00
+	Sc
		355734 H2B2_YEAST (1-131): 1.08e-45: 146: 100.00		SIR3_YEAST (1-914): 0: 587: 26.50
+	Sc
		355296 H2B1_YEAST (1-131): 4.04e-44: 142: 96.95		SIR3_YEAST (1-914): 0: 587: 26.50
+	Hs
		1033387 H2B2E_HUMAN (7-129): 4.62e-47: 149: 70.40		ORC1_HUMAN (155-908): 9.77e-118: 381: 21.21
+	Hs
		217809 H2B2E_HUMAN (7-129): 4.62e-47: 149: 70.40		ORC4_HUMAN (443-840): 4.19e-80: 268: 13.51
+	Sc
		355970 H2B2_YEAST (1-131): 1.08e-45: 146: 100.00		ORC4_YEAST (385-711): 1.69e-45: 174: 13.51
+	Sc
		355586 H2B1_YEAST (1-131): 4.04e-44: 142: 96.95		ORC4_YEAST (385-711): 1.69e-45: 174: 13.51
+	Hs
		875006 H2B2F_HUMAN (7-129): 8.57e-48: 151: 70.40		TERA_HUMAN (420-667): 3.72e-25: 114: 10.00
+	Hs
		875259 H2B1N_HUMAN (7-129): 2.75e-46: 147: 69.60		TERA_HUMAN (420-667): 3.72e-25: 114: 10.00
+	Hs
		177480 H2B1C_HUMAN (7-129): 9.01e-47: 148: 70.40		NVL_HUMAN (333-647): 1.07e-20: 100: 13.68
+	Hs
		722251 H2B2E_HUMAN (7-129): 4.62e-47: 149: 70.40		RFC1_HUMAN (147-633): 9.78e-20: 97.4: 12.66
+	Hs
		707537 H2B1B_HUMAN (7-129): 1.29e-46: 148: 69.60		RFC1_HUMAN (147-633): 9.78e-20: 97.4: 12.66
+	Hs
		722208 H2B1C_HUMAN (7-129): 9.01e-47: 148: 70.40		RFC1_HUMAN (147-633): 9.78e-20: 97.4: 12.66