HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: HP1 (P05205)
Heterochromatin protein 1 (HP1) (Non-histone chromosomal protein C1A9 antigen)
Gene: Su(var)205

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.97	0.60	0.763

Property	Details
Experiments	20889714, 24906153, 18981478, 25613572, 11859155, 11566886, 18846226, 30659116, 31634430, 22052799, 24415761, 23071455, 12897054, unassigned4
Identification Methods	affinity chromatography technology, far western blotting, pull down, unspecified method, fluorescence polarization spectroscopy, experimental interaction detection, filter binding
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005700 - polytene chromosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 206
+	Hs
		934721 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX3_HUMAN (1-206): 2.53e-55: 175: 38.35
+	Hs
		1027017 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX3_HUMAN (1-206): 2.53e-55: 175: 38.35
+	Hs
		800341 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX5_HUMAN (1-206): 1.38e-52: 168: 40.78
+	Hs
		934657 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX1_HUMAN (1-206): 4.02e-52: 167: 36.41
+	Mm
		935445 H31_MOUSE (1-136): 1.98e-62: 189: 99.27		CBX1_MOUSE (1-206): 4.02e-52: 167: 36.41
+	Hs
		800397 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX5_HUMAN (1-206): 1.38e-52: 168: 40.78
+	Hs
		949795 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX1_HUMAN (1-206): 4.02e-52: 167: 36.41
+	Hs
		935237 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV92_HUMAN (5-142): 1.28e-39: 141: 20.00
+	Hs
		934768 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX2_HUMAN (15-187): 6.3e-37: 136: 19.55
+	Hs
		1059154 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX2_HUMAN (15-187): 6.3e-37: 136: 19.55
+	Hs
		203659 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV91_HUMAN (5-141): 9.05e-35: 128: 18.25
+	Hs
		934987 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CDYL2_HUMAN (22-173): 8.53e-33: 124: 25.32
+	Hs
		123231 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX4_HUMAN (14-144): 1.05e-29: 116: 20.41
+	Hs
		123254 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX4_HUMAN (14-144): 1.05e-29: 116: 20.41
+	Hs
		316000 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX6_HUMAN (14-149): 2.78e-29: 114: 24.32
+	Hs
		935387 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CDYL_HUMAN (9-145): 7.36e-29: 114: 24.31
+	Hs
		327837 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX7_HUMAN (14-142): 3.65e-30: 113: 26.36
+	Hs
		316040 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX6_HUMAN (14-149): 2.78e-29: 114: 24.32
+	Hs
		935259 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX8_HUMAN (14-149): 5.69e-29: 112: 22.79
+	Hs
		327844 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX7_HUMAN (14-142): 3.65e-30: 113: 26.36