HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: TRR (Q8IRW8)
Histone-lysine N-methyltransferase trr (EC 2.1.1.354) (Lysine N-methyltransferase 2C) (Trithorax-related protein)
Gene: TRR

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SET
Common GO terms	GO:0005700 - polytene chromosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 2431
+	Hs
		331780 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		NSD2_HUMAN (1798-2430): 1.29e-117: 410: 17.34
+	Hs
		331823 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		NSD2_HUMAN (1798-2430): 1.29e-117: 410: 17.34
+	Hs
		935205 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		NSD3_HUMAN (1786-2430): 6e-102: 364: 15.37
+	Hs
		935126 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		EHMT2_HUMAN (1761-2427): 3.63e-102: 361: 16.50
+	Hs
		935129 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		NSD1_HUMAN (1804-2430): 3.3e-85: 315: 17.31
+	Hs
		203659 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV91_HUMAN (2027-2430): 4.02e-84: 285: 17.70
+	Hs
		934804 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		EZH2_HUMAN (1976-2412): 2.41e-78: 279: 16.60
+	Hs
		935237 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV92_HUMAN (2026-2431): 3.99e-82: 279: 17.87
+	Hs
		935276 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		ASH1L_HUMAN (2120-2430): 4.25e-74: 279: 19.39
+	Hs
		1079993 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		EZH2_HUMAN (1976-2412): 2.41e-78: 279: 16.60
+	Hs
		935251 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		EHMT1_HUMAN (1702-2427): 1.18e-72: 270: 14.79
+	Hs
		935374 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SET1B_HUMAN (2153-2431): 2.86e-68: 259: 27.63
+	Hs
		876688 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		BRPF1_HUMAN (1822-2251): 8.95e-67: 251: 13.16
+	Hs
		165661 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SET1A_HUMAN (2156-2431): 6.41e-66: 250: 26.94
+	Hs
		935204 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SETD2_HUMAN (2240-2430): 1.57e-65: 250: 28.08
+	Hs
		934681 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KMT2A_HUMAN (1892-2224): 4.37e-61: 236: 26.35
+	Hs
		975268 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		KMT2A_HUMAN (1892-2224): 4.37e-61: 236: 26.35
+	Hs
		935368 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KMT2B_HUMAN (1857-2120): 4.9e-51: 203: 29.06
+	Hs
		935004 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KMT2C_HUMAN (1905-2177): 5.73e-11: 70.6: 14.23
+	Hs
		152625 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KMT2D_HUMAN (72-1348): 4.99e-09: 64.5: 8.96