HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: ASF1 (Q9V464)
Histone chaperone asf1 (Anti-silencing function protein 1) (Replication-coupling assembly factor subunit ASF1) (RCAF subunit ASF1) (dASF1)
Gene: ASF1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28320872
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ASF1_hist_chap~Histone
Common GO terms	GO:0005700 - polytene chromosome GO:0035059 - RCAF complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 136 Dm			1 218
+	Hs
		935389 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		ASF1A_HUMAN (1-181): 1.19e-97: 284: 65.19
+	Mm
		935461 H31_MOUSE (1-136): 1.98e-62: 189: 99.27		ASF1A_MOUSE (1-181): 1.35e-97: 284: 65.19
+	Hs
		935298 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		ASF1B_HUMAN (1-154): 3.5e-97: 283: 71.43
+	Hs
		1086358 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		ASF1A_HUMAN (1-181): 1.19e-97: 284: 65.19
+	Hs
		1086330 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		ASF1B_HUMAN (1-154): 3.5e-97: 283: 71.43
+	Hs
		1174696 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		ASF1A_HUMAN (1-181): 1.19e-97: 284: 65.19
+	Mm
		952267 H32_MOUSE (1-136): 3.73e-61: 186: 100.00		ASF1A_MOUSE (1-181): 1.35e-97: 284: 65.19
+	Gg
		952273 H32_CHICK (1-136): 3.73e-61: 186: 100.00		ASF1_CHICK (1-181): 1.19e-97: 284: 65.19
+	Hs
		952711 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		ASF1A_HUMAN (1-181): 1.19e-97: 284: 65.19
+	Mm
		952765 H33_MOUSE (1-136): 1.59e-61: 186: 97.06		ASF1A_MOUSE (1-181): 1.35e-97: 284: 65.19
+	Gg
		952779 H33_CHICK (1-136): 1.59e-61: 186: 97.06		ASF1_CHICK (1-181): 1.19e-97: 284: 65.19
+	Hs
		952660 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		ASF1B_HUMAN (1-154): 3.5e-97: 283: 71.43
+	Mm
		935463 H31_MOUSE (1-136): 1.98e-62: 189: 99.27		ASF1B_MOUSE (1-171): 4.14e-95: 277: 65.50
+	Mm
		952269 H32_MOUSE (1-136): 3.73e-61: 186: 100.00		ASF1B_MOUSE (1-171): 4.14e-95: 277: 65.50
+	Mm
		952769 H33_MOUSE (1-136): 1.59e-61: 186: 97.06		ASF1B_MOUSE (1-171): 4.14e-95: 277: 65.50
+	Sc
		689932 H3_YEAST (1-136): 7.77e-56: 172: 88.97		ASF1_YEAST (1-156): 1.21e-86: 259: 58.33
+	Sp
		251626 H31_SCHPO (1-136): 2.22e-59: 181: 91.91		ASF1_SCHPO (1-154): 5.76e-82: 246: 52.50
+	Hs
		828399 CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00		ASF1B_HUMAN (1-154): 3.5e-97: 283: 71.43