HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: KDM4B (Q9V6L0)
Probable lysine-specific demethylase 4B (EC 1.14.11.66) (Probable JmjC domain-containing histone demethylation protein 3B) (Probable [histone H3]-trimethyl-L-lysine(9) demethylase 4B)
Gene: KDM4B

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19061644
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 590
+	Hs
		301134 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM4B_HUMAN (8-369): 0: 552: 61.58
+	Hs
		301136 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		KDM4B_HUMAN (8-369): 0: 552: 61.58
+	Hs
		301146 H3C_HUMAN (1-136): 8.83e-59: 179: 94.12		KDM4B_HUMAN (8-369): 0: 552: 61.58
+	Hs
		935232 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM4C_HUMAN (3-381): 0: 540: 58.79
+	Hs
		1174653 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		KDM4C_HUMAN (3-381): 0: 540: 58.79
+	Hs
		952622 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		KDM4C_HUMAN (3-381): 0: 540: 58.79
+	Hs
		256961 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM4A_HUMAN (3-357): 1.3e-174: 524: 60.56
+	Hs
		256973 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		KDM4A_HUMAN (3-357): 1.3e-174: 524: 60.56
+	Hs
		256963 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		KDM4A_HUMAN (3-357): 1.3e-174: 524: 60.56
+	Dm
		356095 H3_DROME (1-136): 3.73e-61: 186: 100.00		KDM4A_DROME (2-400): 9.43e-175: 506: 63.12
+	Sp
		457185 H31_SCHPO (1-136): 2.22e-59: 181: 91.91		LID2_SCHPO (37-311): 3.39e-73: 257: 20.34
+	Sp
		498409 H33_SCHPO (1-136): 4.37e-58: 177: 91.18		LID2_SCHPO (37-311): 3.39e-73: 257: 20.34
+	Hs
		666522 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM5A_HUMAN (5-115): 1.31e-14: 79.8: 21.62
+	Hs
		935339 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM5B_HUMAN (5-90): 1.01e-14: 79.8: 26.74
+	Hs
		1086304 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		KDM5D_HUMAN (5-51): 7.69e-15: 80.2: 38.30
+	Hs
		666535 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		KDM5A_HUMAN (5-115): 1.31e-14: 79.8: 21.62
+	Hs
		782353 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		KDM5C_HUMAN (5-51): 6.84e-15: 80.6: 38.30
+	Hs
		666523 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		KDM5A_HUMAN (5-115): 1.31e-14: 79.8: 21.62
+	Hs
		666539 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		KDM5A_HUMAN (5-115): 1.31e-14: 79.8: 21.62
+	Dm
		356114 H3_DROME (1-136): 3.73e-61: 186: 100.00		KDM5_DROME (4-51): 1.52e-14: 79.4: 43.75