HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: Q9VCU6 (Q9VCU6)
Heterochromatin protein 1c (LD23881p)
Gene: HP1c

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.50	0.619

Property	Details
Experiments	20889714, 18981478, 30659116
Identification Methods	affinity chromatography technology, far western blotting, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 237
+	Hs
		935387 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CDYL_HUMAN (2-197): 7.09e-49: 170: 22.11
+	Hs
		123231 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX4_HUMAN (4-202): 4.15e-44: 157: 22.00
+	Hs
		123254 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX4_HUMAN (4-202): 4.15e-44: 157: 22.00
+	Hs
		934721 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX3_HUMAN (4-135): 9.89e-43: 144: 39.46
+	Hs
		1027017 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX3_HUMAN (4-135): 9.89e-43: 144: 39.46
+	Hs
		934987 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CDYL2_HUMAN (1-196): 1.75e-36: 136: 19.43
+	Hs
		800341 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX5_HUMAN (8-155): 5.57e-38: 132: 31.79
+	Hs
		934657 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX1_HUMAN (14-144): 1.27e-37: 131: 35.10
+	Mm
		935445 H31_MOUSE (1-136): 1.98e-62: 189: 99.27		CBX1_MOUSE (14-144): 1.27e-37: 131: 35.10
+	Hs
		800397 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX5_HUMAN (8-155): 5.57e-38: 132: 31.79
+	Hs
		949795 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX1_HUMAN (14-144): 1.27e-37: 131: 35.10
+	Hs
		327837 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX7_HUMAN (4-164): 8.97e-36: 128: 24.85
+	Hs
		327844 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX7_HUMAN (4-164): 8.97e-36: 128: 24.85
+	Hs
		316000 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX6_HUMAN (4-151): 5.58e-32: 122: 23.87
+	Hs
		316040 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX6_HUMAN (4-151): 5.58e-32: 122: 23.87
+	Hs
		935237 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV92_HUMAN (3-125): 5.06e-31: 119: 22.76
+	Hs
		203659 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV91_HUMAN (3-124): 2.33e-30: 118: 22.13
+	Hs
		935259 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX8_HUMAN (4-97): 5.53e-23: 97.6: 28.72
+	Hs
		935156 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		MPP8_HUMAN (5-82): 2.86e-12: 67.7: 36.71
+	Hs
		934768 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX2_HUMAN (5-63): 2.6e-11: 64.7: 42.37