HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: JHD1 (Q9VHH9)
JmjC domain-containing histone demethylation protein 1 (EC 1.14.11.27) (Lysine (K)-specific demethylase 2) ([Histone-H3]-lysine-36 demethylase 1)
Gene: Kdm2

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	18923078
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 1345
+	Hs
		935008 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM2B_HUMAN (42-1322): 0: 1133: 29.87
+	Hs
		1174601 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		KDM2B_HUMAN (42-1322): 0: 1133: 29.87
+	Hs
		952482 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		KDM2B_HUMAN (42-1322): 0: 1133: 29.87
+	Hs
		828308 CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00		KDM2B_HUMAN (42-1322): 0: 1133: 29.87
+	Hs
		935393 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KDM2A_HUMAN (32-1329): 0: 935: 30.59
+	Hs
		1086360 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		KDM2A_HUMAN (32-1329): 0: 935: 30.59
+	Hs
		1174697 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		KDM2A_HUMAN (32-1329): 0: 935: 30.59
+	Hs
		952712 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		KDM2A_HUMAN (32-1329): 0: 935: 30.59
+	Hs
		935373 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		PHF8_HUMAN (34-546): 0: 651: 33.78
+	Hs
		1086352 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		PHF8_HUMAN (34-546): 0: 651: 33.78
+	Hs
		952701 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		PHF8_HUMAN (34-546): 0: 651: 33.78
+	Hs
		1157239 H3C_HUMAN (1-136): 8.83e-59: 179: 94.12		PHF8_HUMAN (34-546): 0: 651: 33.78
+	Hs
		828422 CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00		PHF8_HUMAN (34-546): 0: 651: 33.78
+	Hs
		256400 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		PHF2_HUMAN (34-461): 6.51e-159: 508: 33.18
+	Hs
		256412 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		PHF2_HUMAN (34-461): 6.51e-159: 508: 33.18
+	Hs
		256401 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		PHF2_HUMAN (34-461): 6.51e-159: 508: 33.18
+	Hs
		256416 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		PHF2_HUMAN (34-461): 6.51e-159: 508: 33.18
+	Ce
		445734 H3_CAEEL (1-136): 8.66e-61: 184: 97.06		KDM7_CAEEL (34-453): 1.84e-159: 504: 27.79
+	Hs
		256390 CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00		PHF2_HUMAN (34-461): 6.51e-159: 508: 33.18
+	Sc
		767176 H3_YEAST (1-136): 7.77e-56: 172: 88.97		JHD1_YEAST (34-389): 7.34e-134: 421: 31.71