HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: AURKB (Q9VKN7)
Aurora kinase B (EC 2.7.11.1) (IPL1/Aurora-like protein kinase) (Serine/threonine-protein kinase Ial) (Serine/threonine-protein kinase aurora-B)
Gene: aurB

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	0.50	0.348

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 329
+	Hs
		682163 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		AKT2_HUMAN (1-328): 1.13e-139: 405: 27.46
+	Hs
		610712 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		KAPCB_HUMAN (31-327): 2.27e-134: 387: 30.46
+	Hs
		610715 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		KAPCB_HUMAN (31-327): 2.27e-134: 387: 30.46
+	Hs
		610742 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		KAPCB_HUMAN (31-327): 2.27e-134: 387: 30.46
+	Hs
		160506 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		AURKA_HUMAN (1-325): 7.47e-130: 377: 43.47
+	Hs
		160599 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		AURKA_HUMAN (1-325): 7.47e-130: 377: 43.47
+	Mm
		952738 H33_MOUSE (1-136): 1.59e-61: 186: 97.06		AURKA_MOUSE (2-326): 2.97e-129: 376: 44.00
+	Dm
		356080 H3_DROME (1-136): 3.73e-61: 186: 100.00		Q27393_DROME (35-309): 3.3e-125: 366: 49.09
+	Hs
		935379 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		AURKC_HUMAN (52-307): 1.29e-95: 287: 51.56
+	Mm
		250432 H33_MOUSE (1-136): 1.59e-61: 186: 97.06		AURKB_MOUSE (44-307): 3.07e-93: 282: 50.00
+	Hs
		935110 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		AURKB_HUMAN (52-307): 1.99e-90: 275: 52.34
+	Hs
		1086273 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		AURKB_HUMAN (52-307): 1.99e-90: 275: 52.34
+	Hs
		1174628 H32_HUMAN (1-136): 3.73e-61: 186: 100.00		AURKB_HUMAN (52-307): 1.99e-90: 275: 52.34
+	Hs
		952545 H33_HUMAN (1-136): 1.59e-61: 186: 97.06		AURKB_HUMAN (52-307): 1.99e-90: 275: 52.34
+	At
		886668 H31_ARATH (1-136): 9.88e-61: 184: 97.06		AUR1_ARATH (48-305): 1.18e-89: 271: 51.54
+	Hs
		1157219 H3C_HUMAN (1-136): 8.83e-59: 179: 94.12		AURKB_HUMAN (52-307): 1.99e-90: 275: 52.34
+	Hs
		828423 CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00		AURKC_HUMAN (52-307): 1.29e-95: 287: 51.56
+	Hs
		828344 CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00		AURKB_HUMAN (52-307): 1.99e-90: 275: 52.34
+	Sc
		758807 H3_YEAST (1-136): 7.77e-56: 172: 88.97		IPL1_YEAST (3-305): 7.18e-73: 231: 42.81
+	Sc
		730798 CENPA_YEAST (18-134): 1.58e-41: 139: 56.67		IPL1_YEAST (3-305): 7.18e-73: 231: 42.81