HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: CSK22 (P19454)
Casein kinase II subunit alpha' (CK II) (EC 2.7.11.1)
Gene: CKA2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	16135807, 32064518, 37968396, 22199229, 21179020
Identification Methods	enzymatic study, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0042790 - nucleolar large rRNA transcription by RNA polymerase I
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 339
+	Hs
		625319 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CDK2_HUMAN (47-335): 6.33e-123: 356: 27.67
+	Hs
		835635 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		GSK3B_HUMAN (4-339): 3.77e-117: 346: 26.78
+	Hs
		414849 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CDK1_HUMAN (47-337): 1.49e-116: 340: 28.05
+	Sc
		356221 H4_YEAST (1-103): 5.28e-47: 147: 100.00		CSK21_YEAST (14-334): 3.73e-104: 311: 50.55
+	Hs
		835309 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		GSK3A_HUMAN (2-334): 5.19e-104: 315: 30.23