HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: SPT6 (P23615)
Transcription elongation factor SPT6 (Chromatin elongation factor SPT6)
Gene: SPT6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	25182531, 37968396, 21179020
Identification Methods	unspecified method, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0006334 - nucleosome assembly
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 1451
+	Zm
		37140 B4FD59_MAIZE (18-103): 5.22e-41: 132: 89.54		A0A1D6M795_MAIZE (57-1436): 0: 1038: 22.64
+	Hs
		917489 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SPT6H_HUMAN (54-1439): 0: 1026: 21.77
+	Dm
		950425 H4_DROME (18-103): 2.42e-41: 133: 90.70		SPT6H_DROME (20-1438): 0: 986: 21.75
+	Hs
		917592 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SRBD1_HUMAN (177-1204): 0: 618: 14.91
+	Sc
		356778 H4_YEAST (1-103): 5.28e-47: 147: 100.00		MDN1_YEAST (4-423): 6.48e-16: 86.2: 14.18
+	Hs
		918011 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		MDN1_HUMAN (33-712): 9.31e-16: 85.8: 10.59