HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: MCM5 (P29496)
Minichromosome maintenance protein 5 (EC 3.6.4.12) (Cell division control protein 46)
Gene: MCM5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	19106085, 21179020, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031298 - replication fork protection complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 775
+	Hs
		708595 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		MCM5_HUMAN (3-772): 0: 760: 46.21
+	Hs
		832321 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		MCM2_HUMAN (2-774): 0: 675: 27.72
+	Sc
		356306 H4_YEAST (1-103): 5.28e-47: 147: 100.00		MCM4_YEAST (19-747): 0: 659: 28.05
+	Hs
		917263 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		MCM6_HUMAN (5-767): 0: 646: 26.49
+	Hs
		708413 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		MCM4_HUMAN (1-759): 0: 645: 28.93
+	Hs
		708859 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		MCM7_HUMAN (23-770): 0: 641: 28.11
+	Sc
		356602 H4_YEAST (1-103): 5.28e-47: 147: 100.00		MCM6_YEAST (17-717): 0: 625: 26.09
+	Sc
		356302 H4_YEAST (1-103): 5.28e-47: 147: 100.00		MCM2_YEAST (27-691): 7.37e-92: 308: 31.78