HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: HIR2 (P32480)
Protein HIR2 (Histone transcription regulator 2)
Gene: HIR2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	14651846, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0006334 - nucleosome assembly
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 875
+	Sc
		356326 H4_YEAST (1-103): 5.28e-47: 147: 100.00		HIR1_YEAST (1-542): 6.88e-84: 288: 17.77
+	Dm
		53061 H4_DROME (18-103): 2.42e-41: 133: 90.70		A1Z898_DROME (7-513): 3.11e-72: 254: 14.21
+	Sc
		356699 H4_YEAST (1-103): 5.28e-47: 147: 100.00		CAC2_YEAST (63-409): 1.11e-58: 209: 18.80
+	Hs
		903099 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		WDR5_HUMAN (4-350): 6.32e-53: 189: 11.68
+	Hs
		917174 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TBL3_HUMAN (2-435): 3.53e-45: 176: 9.56
+	Hs
		867848 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HIRA_HUMAN (202-540): 5.57e-28: 123: 10.24
+	Hs
		917886 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		WDR33_HUMAN (149-419): 3.59e-23: 108: 10.26
+	Hs
		917881 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TBL1R_HUMAN (386-749): 1.18e-19: 95.3: 9.65
+	Hs
		245586 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TBL1X_HUMAN (504-752): 1.23e-14: 79.9: 9.38
+	Hs
		917196 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CAF1B_HUMAN (267-425): 9.95e-11: 67.3: 8.56