HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: SET5 (P38890)
Histone-lysine N-methyltransferase SET5 (EC 2.1.1.-) (SET domain-containing protein 5)
Gene: SET5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.899

Property	Details
Experiments	22343720, 31685550, 22688645, 21179020
Identification Methods	methyltransferase assay, enzymatic study, tandem affinity purification
Interaction Type	direct interaction, methylation reaction, association

Property	Details
Interacting Pfam domains	CENP-T_C~SET
Common GO terms	GO:0005634 - nucleus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 526
+	Hs
		917439 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SMYD5_HUMAN (114-435): 4.84e-67: 224: 19.95
+	Hs
		917928 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SMYD3_HUMAN (113-456): 3.48e-63: 214: 21.90
+	Sc
		356807 H4_YEAST (1-103): 5.28e-47: 147: 100.00		SET6_YEAST (124-435): 7.08e-53: 185: 16.11