HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: CAC2 (Q04199)
Chromatin assembly factor 1 subunit p60 (CAF-1 60 kDa subunit)
Gene: CAC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	21256037, 21444721, 23034810, 24209620
Identification Methods	tandem affinity purification, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0006334 - nucleosome assembly
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 468
+	Hs
		917196 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CAF1B_HUMAN (1-466): 5.47e-82: 265: 31.08
+	Dm
		53061 H4_DROME (18-103): 2.42e-41: 133: 90.70		A1Z898_DROME (1-462): 3.9e-78: 260: 28.78
+	Hs
		917702 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		FBXW7_HUMAN (173-463): 1.41e-45: 170: 12.46
+	Hs
		917722 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		SNR40_HUMAN (179-461): 4.29e-39: 146: 11.15
+	Sc
		356326 H4_YEAST (1-103): 5.28e-47: 147: 100.00		HIR1_YEAST (1-363): 5.13e-25: 110: 11.52
+	Hs
		917881 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TBL1R_HUMAN (182-401): 7.51e-25: 109: 12.01
+	Hs
		245586 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TBL1X_HUMAN (182-436): 1.13e-23: 106: 14.72
+	Hs
		867848 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HIRA_HUMAN (6-231): 8.55e-23: 104: 13.16
+	Hs
		903099 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		WDR5_HUMAN (2-99): 4.14e-11: 66: 17.82