HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: BDF2 (Q07442)
Bromodomain-containing factor 2
Gene: BDF2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	11805826, 37968396, 22199229, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 638
+	Sp
		448927 H4_SCHPO (18-103): 2.79e-41: 133: 90.70		YK82_SCHPO (4-626): 1.53e-99: 321: 21.67
+	Sc
		356398 H4_YEAST (1-103): 5.28e-47: 147: 100.00		BDF1_YEAST (60-631): 1.57e-89: 294: 36.20
+	Hs
		917657 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		PHIP_HUMAN (85-520): 8.11e-65: 234: 17.05
+	Hs
		600119 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TAF1_HUMAN (79-638): 1.5e-57: 212: 14.53
+	Hs
		917576 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TAF1L_HUMAN (79-603): 1.03e-51: 195: 14.21
+	Dm
		950390 H4_DROME (18-103): 2.42e-41: 133: 90.70		Q4V5A7_DROME (109-534): 1.03e-48: 182: 17.05
+	Zm
		19319 A0A1D6IAU4_MAIZE (18-103): 9.75e-45: 142: 89.54		A0A1D6HCG5_MAIZE (7-294): 2.68e-37: 149: 18.52
+	Mm
		918262 H4_MOUSE (18-103): 1.92e-41: 133: 90.70		BRDT_MOUSE (3-282): 3.64e-34: 141: 19.08
+	Hs
		917299 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRD3_HUMAN (296-491): 2.95e-27: 119: 20.41
+	Hs
		244235 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRD4_HUMAN (278-457): 1.37e-25: 114: 22.22
+	Hs
		631388 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRD2_HUMAN (445-637): 1.38e-24: 111: 14.21
+	Hs
		917517 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		PB1_HUMAN (65-329): 8.02e-20: 96.7: 12.41
+	Hs
		917466 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		BRWD3_HUMAN (77-314): 3.87e-19: 94.4: 13.36
+	Dm
		532730 H4_DROME (18-103): 2.42e-41: 133: 90.70		FSH_DROME (496-614): 3.4e-17: 88.4: 26.05
+	Hs
		917684 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CBP_HUMAN (312-419): 1.36e-12: 73.6: 37.62
+	Hs
		917170 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		EP300_HUMAN (342-419): 4.06e-12: 72: 44.87
+	Hs
		999008 H4G_HUMAN (1-98): 1.23e-37: 123: 77.55		EP300_HUMAN (342-419): 4.06e-12: 72: 44.87