HitPredict

Interactor 1: P53 (P02340)
Cellular tumor antigen p53 (Tumor suppressor p53)
Gene: Tp53

Interactor 2: CBP (P45481)
Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: Crebbp

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 9194565
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Creb_binding~P53_TAD, P53_TAD~zf-TAZ
Common GO terms GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 12 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 390
Mm

1 2441
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024