HitPredict - High confidence protein-protein interactions

Interactor 1: P53 (P02340)
Cellular tumor antigen p53 (Tumor suppressor p53)
Gene: Tp53

Interactor 2: NPM (Q61937)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: Npm1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17277230
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002039 - p53 binding GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 16 others more... GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0008285 - negative regulation of cell population proliferation GO:0009303 - rRNA transcription GO:0010629 - negative regulation of gene expression GO:0016363 - nuclear matrix GO:0043066 - negative regulation of apoptotic process GO:0043516 - regulation of DNA damage response, signal transduction by p53 class mediator GO:0043523 - regulation of neuron apoptotic process GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0050821 - protein stabilization GO:0051726 - regulation of cell cycle GO:0090398 - cellular senescence
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	390
Mm

1	292

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024