Interactor 1: CO1A1 (P02452)
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
Gene: COL1A1

Interactor 2: CO1A2 (P08123)
Collagen alpha-2(I) chain (Alpha-2 type I collagen)
Gene: COL1A2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 24981860, 18375391, 26848503
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains COLFI~COLFI, Collagen~Collagen
Common GO terms GO:0001501 - skeletal system development
GO:0001568 - blood vessel development
GO:0002020 - protease binding
GO:0005576 - extracellular region
GO:0005584 - collagen type I trimer
and 11 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1464
Hs

1 1366
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm

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Last updated: 15 Jul 2024