HitPredict

Interactor 1: CO1A1 (P02452)
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
Gene: COL1A1

Interactor 2: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26848503
Identification Methods	anti tag coimmunoprecipitation, cross-linking study
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005788 - endoplasmic reticulum lumen
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1464 Hs			1 645
+	Hs
		358447 CO1A1_HUMAN (1-1464): 0: 674: 100.00		PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11
+	Hs
		358517 CO1A1_HUMAN (1-1464): 0: 674: 100.00		PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51
+	Hs
		358484 CO1A1_HUMAN (1-1464): 0: 674: 100.00		PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35
+	Hs
		358537 CO1A1_HUMAN (1-1464): 0: 674: 100.00		TXND5_HUMAN (547-631): 1.03e-21: 100: 34.48
+	Hs
		531799 CO4A3_HUMAN (901-1256): 6.96e-21: 102: 35.66		PDIA4_HUMAN (1-645): 0: 571: 100.00
+	Oc
		101995 G1T2Z5_RABIT (1-1099): 2.73e-135: 453: 42.26		PDIA1_RABIT (4-165): 2.27e-33: 136: 27.11
+	Hs
		358607 CO2A1_HUMAN (3-246): 5.59e-17: 89.5: 27.24		PDIA2_HUMAN (62-504): 2.13e-45: 171: 16.56
+	Hs
		518048 CO6A3_HUMAN (109-231): 8.15e-11: 69.3: 37.41		PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35