HitPredict

Interactor 1: CO1A1 (P02452)
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
Gene: COL1A1

Interactor 2: IBP3 (P17936)
Insulin-like growth factor-binding protein 3 (IBP-3) (IGF-binding protein 3) (IGFBP-3)
Gene: IGFBP3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.581

Property	Details
Experiments	12735930
Identification Methods	affinity chromatography technology, biochemical, two hybrid
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001649 - osteoblast differentiation GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005788 - endoplasmic reticulum lumen GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1464 Hs			1 291
+	Hs
		358511 CO1A1_HUMAN (1-1464): 0: 674: 100.00		NID2_HUMAN (23-277): 2.82e-41: 153: 18.42
+	Hs
		358545 CO1A1_HUMAN (1-1464): 0: 674: 100.00		HTRA1_HUMAN (24-173): 2.67e-37: 139: 24.34
+	Hs
		358465 CO1A1_HUMAN (1-1464): 0: 674: 100.00		NID1_HUMAN (32-212): 7.7e-15: 76.5: 13.30
+	Hs
		358662 CO4A1_HUMAN (6-554): 2.86e-65: 247: 33.56		NID2_HUMAN (23-277): 2.82e-41: 153: 18.42
+	Hs
		358649 CO4A1_HUMAN (6-554): 2.86e-65: 247: 33.56		NID1_HUMAN (32-212): 7.7e-15: 76.5: 13.30