HitPredict

Interactor 1: CO1A1 (P02452)
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
Gene: COL1A1

Interactor 2: PLOD1 (Q02809)
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1)
Gene: PLOD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.50	0.604

Property	Details
Experiments	28514442, 33961781, 26848503
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1464 Hs			1 727
+	Hs
		129876 CO1A1_HUMAN (1-1464): 0: 674: 100.00		PLOD2_HUMAN (13-727): 0: 1209: 60.06
+	Hs
		237005 CO1A1_HUMAN (1-1464): 0: 674: 100.00		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		358661 CO4A1_HUMAN (6-554): 2.86e-65: 247: 33.56		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		862503 CO4A4_HUMAN (20-1011): 1.16e-51: 203: 34.62		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		237006 CO4A1_HUMAN (6-554): 2.86e-65: 247: 33.56		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		596157 CO5A1_HUMAN (3-654): 6.99e-36: 151: 36.76		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		972738 CO4A6_HUMAN (8-289): 5.07e-23: 109: 25.25		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		358604 CO2A1_HUMAN (3-246): 5.59e-17: 89.5: 27.24		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		972727 COGA1_HUMAN (988-1266): 1.29e-11: 71.8: 23.34		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		441060 CO4A2_HUMAN (3-160): 2e-11: 71.4: 21.95		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		237052 CO4A6_HUMAN (8-289): 5.07e-23: 109: 25.25		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		237048 COGA1_HUMAN (988-1266): 1.29e-11: 71.8: 23.34		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		237016 CO4A2_HUMAN (3-160): 2e-11: 71.4: 21.95		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Dm
		435988 CO4A1_DROME (5-476): 1.38e-55: 215: 28.92		PLOD_DROME (15-727): 0: 1029: 43.75
+	Hs
		358533 CO1A1_HUMAN (1-1464): 0: 674: 100.00		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		358536 CO1A1_HUMAN (1-1464): 0: 674: 100.00		GT251_HUMAN (286-535): 8.83e-93: 303: 24.20
+	Hs
		358664 CO4A1_HUMAN (6-554): 2.86e-65: 247: 33.56		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		358613 CO2A1_HUMAN (3-246): 5.59e-17: 89.5: 27.24		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		990783 COGA1_HUMAN (988-1266): 1.29e-11: 71.8: 23.34		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		441073 CO4A2_HUMAN (3-160): 2e-11: 71.4: 21.95		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48