Interactor 1: CO1A1 (P02452)
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
Gene: COL1A1

Interactor 2: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.534

The method score is based on:

Property Details
Experiments 19558215
Identification Methods electrophoretic mobility supershift assay, anti tag coimmunoprecipitation, nucleic acid uv cross-linking assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001649 - osteoblast differentiation
GO:0005737 - cytoplasm
GO:0010718 - positive regulation of epithelial to mesenchymal transition
GO:0045893 - positive regulation of DNA-templated transcription
GO:0046872 - metal ion binding
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1464
Hs

1 552
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024