HitPredict

Interactor 1: CO1A1 (P02452)
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
Gene: COL1A1

Interactor 2: GT251 (Q8NBJ5)
Procollagen galactosyltransferase 1 (EC 2.4.1.50) (Collagen beta(1-O)galactosyltransferase 1) (ColGalT 1) (Glycosyltransferase 25 family member 1) (Hydroxylysine galactosyltransferase 1)
Gene: COLGALT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26848503
Identification Methods	cross-linking study, anti tag coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen GO:0030199 - collagen fibril organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1464 Hs			1 622
+	Hs
		358533 CO1A1_HUMAN (1-1464): 0: 674: 100.00		GT252_HUMAN (45-622): 0: 878: 66.78
+	Hs
		358664 CO4A1_HUMAN (6-554): 2.86e-65: 247: 33.56		GT252_HUMAN (45-622): 0: 878: 66.78
+	Hs
		237005 CO1A1_HUMAN (1-1464): 0: 674: 100.00		PLOD3_HUMAN (26-328): 1.67e-93: 305: 22.98
+	Hs
		358613 CO2A1_HUMAN (3-246): 5.59e-17: 89.5: 27.24		GT252_HUMAN (45-622): 0: 878: 66.78
+	Hs
		990783 COGA1_HUMAN (988-1266): 1.29e-11: 71.8: 23.34		GT252_HUMAN (45-622): 0: 878: 66.78
+	Hs
		441073 CO4A2_HUMAN (3-160): 2e-11: 71.4: 21.95		GT252_HUMAN (45-622): 0: 878: 66.78
+	Hs
		358499 CO1A1_HUMAN (1-1464): 0: 674: 100.00		PLOD1_HUMAN (32-328): 1.94e-80: 270: 22.77
+	Hs
		129876 CO1A1_HUMAN (1-1464): 0: 674: 100.00		PLOD2_HUMAN (26-291): 7.03e-78: 263: 23.55
+	Hs
		237006 CO4A1_HUMAN (6-554): 2.86e-65: 247: 33.56		PLOD3_HUMAN (26-328): 1.67e-93: 305: 22.98
+	Hs
		358661 CO4A1_HUMAN (6-554): 2.86e-65: 247: 33.56		PLOD1_HUMAN (32-328): 1.94e-80: 270: 22.77
+	Hs
		862503 CO4A4_HUMAN (20-1011): 1.16e-51: 203: 34.62		PLOD1_HUMAN (32-328): 1.94e-80: 270: 22.77
+	Dm
		435988 CO4A1_DROME (5-476): 1.38e-55: 215: 28.92		PLOD_DROME (33-293): 8.4e-67: 233: 28.30
+	Hs
		596157 CO5A1_HUMAN (3-654): 6.99e-36: 151: 36.76		PLOD1_HUMAN (32-328): 1.94e-80: 270: 22.77
+	Hs
		237052 CO4A6_HUMAN (8-289): 5.07e-23: 109: 25.25		PLOD3_HUMAN (26-328): 1.67e-93: 305: 22.98
+	Hs
		972738 CO4A6_HUMAN (8-289): 5.07e-23: 109: 25.25		PLOD1_HUMAN (32-328): 1.94e-80: 270: 22.77
+	Hs
		237048 COGA1_HUMAN (988-1266): 1.29e-11: 71.8: 23.34		PLOD3_HUMAN (26-328): 1.67e-93: 305: 22.98
+	Hs
		237016 CO4A2_HUMAN (3-160): 2e-11: 71.4: 21.95		PLOD3_HUMAN (26-328): 1.67e-93: 305: 22.98
+	Hs
		358604 CO2A1_HUMAN (3-246): 5.59e-17: 89.5: 27.24		PLOD1_HUMAN (32-328): 1.94e-80: 270: 22.77
+	Hs
		972727 COGA1_HUMAN (988-1266): 1.29e-11: 71.8: 23.34		PLOD1_HUMAN (32-328): 1.94e-80: 270: 22.77
+	Hs
		441060 CO4A2_HUMAN (3-160): 2e-11: 71.4: 21.95		PLOD1_HUMAN (32-328): 1.94e-80: 270: 22.77