HitPredict

Interactor 1: CO2A1 (P02458)
Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin]
Gene: COL2A1

Interactor 2: PLOD1 (Q02809)
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1)
Gene: PLOD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.50	0.567

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1487 Hs			1 727
+	Hs
		358499 CO1A1_HUMAN (3-762): 1.62e-71: 266: 41.28		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		972738 CO4A6_HUMAN (538-1295): 8.9e-71: 264: 31.78		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		441060 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		862503 CO4A4_HUMAN (3-1059): 8.17e-64: 242: 32.12		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		129876 CO1A1_HUMAN (3-762): 1.62e-71: 266: 41.28		PLOD2_HUMAN (13-727): 0: 1209: 60.06
+	Hs
		237005 CO1A1_HUMAN (3-762): 1.62e-71: 266: 41.28		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		237052 CO4A6_HUMAN (538-1295): 8.9e-71: 264: 31.78		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		358661 CO4A1_HUMAN (3-500): 1.73e-52: 205: 34.80		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		237016 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		596157 CO5A1_HUMAN (10-712): 3.99e-49: 194: 36.90		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		237006 CO4A1_HUMAN (3-500): 1.73e-52: 205: 34.80		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		972727 COGA1_HUMAN (3-381): 3.06e-14: 80.6: 29.31		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		237048 COGA1_HUMAN (3-381): 3.06e-14: 80.6: 29.31		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Dm
		435988 CO4A1_DROME (3-477): 1.29e-55: 215: 30.32		PLOD_DROME (15-727): 0: 1029: 43.75
+	Hs
		358613 CO2A1_HUMAN (1-1487): 0: 779: 100.00		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		358533 CO1A1_HUMAN (3-762): 1.62e-71: 266: 41.28		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		358536 CO1A1_HUMAN (3-762): 1.62e-71: 266: 41.28		GT251_HUMAN (286-535): 8.83e-93: 303: 24.20
+	Hs
		441073 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		358664 CO4A1_HUMAN (3-500): 1.73e-52: 205: 34.80		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		990783 COGA1_HUMAN (3-381): 3.06e-14: 80.6: 29.31		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48