HitPredict

Interactor 1: CO2A1 (P02458)
Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin]
Gene: COL2A1

Interactor 2: Q4VAQ0 (Q4VAQ0)
COL8A2 protein
Gene: COL8A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Collagen~Collagen
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1487 Hs			1 427
+	Hs
		358617 CO2A1_HUMAN (1-1487): 0: 779: 100.00		C1QT1_HUMAN (251-424): 6.23e-40: 145: 26.26
+	Hs
		358582 CO2A1_HUMAN (1-1487): 0: 779: 100.00		C1QC_HUMAN (202-426): 1.32e-38: 141: 31.86
+	Hs
		358599 CO2A1_HUMAN (1-1487): 0: 779: 100.00		CO8A2_HUMAN (44-343): 6.59e-17: 84.9: 28.33
+	Hs
		358596 CO2A1_HUMAN (1-1487): 0: 779: 100.00		CO9A1_HUMAN (76-258): 2.18e-16: 83.6: 46.15
+	Hs
		358590 CO2A1_HUMAN (1-1487): 0: 779: 100.00		C1T9A_HUMAN (2-160): 1.91e-15: 78.8: 23.90
+	Hs
		358600 CO2A1_HUMAN (1-1487): 0: 779: 100.00		CO8A1_HUMAN (76-335): 6.74e-15: 78.8: 36.26
+	Hs
		358618 CO2A1_HUMAN (1-1487): 0: 779: 100.00		C1QT2_HUMAN (18-109): 2.17e-09: 60.3: 27.17
+	Hs
		70495 CO2A1_HUMAN (1-1487): 0: 779: 100.00		C1T9B_HUMAN (231-342): 4.7e-09: 59.5: 16.52
+	Hs
		358641 CO3A1_HUMAN (1-1487): 1.29e-178: 574: 59.76		C1QT1_HUMAN (251-424): 6.23e-40: 145: 26.26
+	Dm
		435987 Q9VMV5_DROME (2-886): 1.88e-103: 368: 35.26		CO4A1_DROME (186-345): 1.24e-10: 65.7: 27.33
+	Hs
		1047979 CO4A6_HUMAN (538-1295): 8.9e-71: 264: 31.78		Q4VAQ0_HUMAN (1-427): 4.88e-45: 163: 100.00
+	Hs
		1047982 CO4A6_HUMAN (538-1295): 8.9e-71: 264: 31.78		C1QT1_HUMAN (251-424): 6.23e-40: 145: 26.26
+	Hs
		362576 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		C1QC_HUMAN (202-426): 1.32e-38: 141: 31.86
+	Hs
		358479 CO1A1_HUMAN (3-762): 1.62e-71: 266: 41.28		CO8A2_HUMAN (44-343): 6.59e-17: 84.9: 28.33
+	Hs
		626312 CO4A6_HUMAN (538-1295): 8.9e-71: 264: 31.78		CO8A2_HUMAN (44-343): 6.59e-17: 84.9: 28.33
+	Hs
		441057 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		CO8A2_HUMAN (44-343): 6.59e-17: 84.9: 28.33
+	Hs
		441055 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		CO9A1_HUMAN (76-258): 2.18e-16: 83.6: 46.15
+	Hs
		441048 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		C1T9A_HUMAN (2-160): 1.91e-15: 78.8: 23.90
+	Hs
		358648 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		CO4A1_HUMAN (5-355): 3.03e-11: 67.6: 21.82
+	Hs
		362501 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		C1QB_HUMAN (32-86): 5.43e-10: 61.4: 27.27