Interactor 1: CRYAB (P02511)
Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Heat shock protein family B member 5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component)
Gene: CRYAB
Interactor 2: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.984 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28919577, 11700327, 17916631, 18330356, 26186194, 28514442, 1560006, 33961781, 12601044, 20863832, 23188086, 23532854 |
| Identification Methods | pull down, two hybrid, affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, nuclear magnetic resonance |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Crystallin~HSP20, HSP20~HSP20 |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0009408 - response to heat GO:0030018 - Z disc and 5 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
