HitPredict

Interactor 1: CRYAB (P02511)
Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Heat shock protein family B member 5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component)
Gene: CRYAB

Interactor 2: VEGFA (P15692)
Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA]
Gene: VEGFA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

The method score is based on:

Property	Details
Experiments	21984182, 17487982
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001666 - response to hypoxia GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0009986 - cell surface GO:0010629 - negative regulation of gene expression and 2 others more... GO:0042803 - protein homodimerization activity GO:0043066 - negative regulation of apoptotic process
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	175
Hs

1	395

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024