HitPredict

Interactor 1: CRYAB (P02511)
Alpha-crystallin B chain (Alpha(B)-crystallin) (Heat shock protein beta-5) (HspB5) (Heat shock protein family B member 5) (Renal carcinoma antigen NY-REN-27) (Rosenthal fiber component)
Gene: CRYAB

Interactor 2: HSPB2 (Q16082)
Heat shock protein beta-2 (HspB2) (DMPK-binding protein) (MKBP) (Heat shock protein family B member 2)
Gene: HSPB2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.929

The method score is based on:

Property Details
Experiments 26465331, 10625651, 12601044, 23188086, 23532854
Identification Methods two hybrid, affinity chromatography technology, pull down, nuclear magnetic resonance
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Crystallin~Crystallin, Crystallin~HSP20, HSP20~HSP20
Common GO terms GO:0005212 - structural constituent of eye lens
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009408 - response to heat
and 3 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 175
Hs

1 182
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+ Bt
+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024