Interactor 1: K1C14 (P02533)
Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)
Gene: KRT14
Interactor 2: K2C5 (P13647)
Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5)
Gene: KRT5
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.65 | 1.00 | 0.809 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22705788 |
| Identification Methods | x-ray crystallography, ion exchange chromatography, transmission electron microscopy, pull down, cosedimentation in solution, comigration in sds page |
| Interaction Type | covalent binding, physical association, direct interaction, disulfide bond |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Filament~Filament |
| Common GO terms | GO:0005200 - structural constituent of cytoskeleton GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005882 - intermediate filament and 4 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
