HitPredict

Interactor 1: K1C14 (P02533)
Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)
Gene: KRT14

Interactor 2: TCHP (Q9BT92)
Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin) (Tumor suppressor protein)
Gene: TCHP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	15731013
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045095 - keratin filament
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 472 Hs			1 498
+	Hs
		445110 K1C16_HUMAN (1-441): 3.53e-146: 427: 84.42		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		444469 K1C19_HUMAN (104-428): 1.03e-145: 424: 69.23		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		580090 K1C15_HUMAN (114-468): 8.15e-137: 403: 68.82		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		280707 KRT34_HUMAN (108-426): 1.34e-121: 362: 58.31		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		724787 K1C17_HUMAN (108-470): 1.08e-144: 422: 82.37		MYH9_HUMAN (12-482): 7.23e-12: 70.1: 12.68
+	Hs
		725143 K1C17_HUMAN (108-470): 1.08e-144: 422: 82.37		MYH10_HUMAN (13-495): 1.16e-11: 69.7: 10.77
+	Hs
		1189645 K1C27_HUMAN (31-472): 2.58e-142: 417: 51.23		CP250_HUMAN (22-497): 3.85e-11: 68.2: 15.21
+	Hs
		318873 K2C75_HUMAN (3-437): 1.6e-87: 279: 27.46		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		1071336 K1H1_HUMAN (75-441): 4.71e-138: 405: 53.93		CFA53_HUMAN (141-495): 4.49e-11: 67: 14.37
+	Hs
		1071283 K1H1_HUMAN (75-441): 4.71e-138: 405: 53.93		GG6L2_HUMAN (16-365): 7.73e-09: 60.5: 13.39
+	Hs
		1270301 KRT35_HUMAN (2-434): 1.15e-79: 256: 51.04		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		1055193 K1H2_HUMAN (31-435): 5.77e-78: 252: 49.14		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		359528 K2C6A_HUMAN (23-445): 8.97e-75: 247: 25.18		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		531622 K2C5_HUMAN (80-429): 1.41e-74: 247: 26.99		TCHP_HUMAN (1-498): 6.62e-60: 206: 100.00
+	Hs
		1055068 KT33B_HUMAN (108-443): 3.43e-125: 371: 57.44		GG6L2_HUMAN (16-365): 7.73e-09: 60.5: 13.39
+	Hs
		280692 KRT34_HUMAN (108-426): 1.34e-121: 362: 58.31		CFA53_HUMAN (141-495): 4.49e-11: 67: 14.37