HitPredict

Interactor 1: K2C6A (P02538)
Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5)
Gene: KRT6A

Interactor 2: TRI23 (P36406)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: TRIM23

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.654

Property	Details
Experiments	25416956, 25910212
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid bait and prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 564 Hs			1 574
+	Hs
		380572 K2C1_HUMAN (128-494): 4.07e-107: 336: 73.30		TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00
+	Hs
		318781 K2C75_HUMAN (3-564): 4.11e-101: 318: 67.79		TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00
+	Hs
		729066 K22E_HUMAN (135-479): 3.33e-173: 506: 72.75		ARF5_HUMAN (392-568): 1.63e-69: 223: 55.37
+	Hs
		734597 K22O_HUMAN (4-491): 3.07e-71: 242: 63.01		TRI23_HUMAN (1-574): 1.73e-139: 418: 100.00
+	Hs
		380591 K2C1_HUMAN (128-494): 4.07e-107: 336: 73.30		ARF1_HUMAN (390-569): 5.89e-71: 227: 57.22
+	Hs
		380592 K2C1_HUMAN (128-494): 4.07e-107: 336: 73.30		ARF5_HUMAN (392-568): 1.63e-69: 223: 55.37
+	Hs
		318903 K2C75_HUMAN (3-564): 4.11e-101: 318: 67.79		TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51
+	Hs
		531552 K2C5_HUMAN (3-479): 1.58e-84: 276: 80.75		ARF5_HUMAN (392-568): 1.63e-69: 223: 55.37
+	Hs
		965463 K22O_HUMAN (4-491): 3.07e-71: 242: 63.01		TRIM1_HUMAN (21-400): 5.38e-69: 238: 19.51