HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: ZSC22 (P10073)
Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50)
Gene: ZSCAN22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 491
+	Hs
		360580 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC21_HUMAN (1-461): 7.27e-157: 455: 38.03
+	Hs
		360243 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC4_HUMAN (9-490): 1.43e-154: 452: 36.79
+	Hs
		359633 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZNF3_HUMAN (123-463): 2.27e-136: 402: 42.57
+	Hs
		360385 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN436_HUMAN (211-490): 5.23e-133: 395: 47.06
+	Hs
		359941 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN345_HUMAN (100-381): 2.52e-95: 298: 25.51
+	Hs
		535557 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZN436_HUMAN (211-490): 5.23e-133: 395: 47.06
+	Hs
		422285 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZN436_HUMAN (211-490): 5.23e-133: 395: 47.06
+	Hs
		422312 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZN180_HUMAN (95-383): 4.2e-103: 324: 22.95
+	Hs
		360346 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC3_HUMAN (119-321): 6.01e-46: 169: 16.39
+	Hs
		360070 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZFP2_HUMAN (254-403): 7.96e-45: 165: 54.67
+	Hs
		67847 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN724_HUMAN (46-222): 3.95e-43: 163: 10.00
+	Hs
		359978 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC8_HUMAN (100-267): 2.5e-42: 160: 9.94
+	Hs
		485160 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZSC22_HUMAN (317-490): 2.94e-86: 275: 59.77
+	Hs
		200800 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC12_HUMAN (100-248): 8.33e-16: 82.2: 9.87
+	Hs
		359631 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC1_HUMAN (100-224): 5.3e-14: 76.5: 12.50
+	Hs
		360017 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN569_HUMAN (46-133): 1.89e-09: 62.1: 6.59
+	Hs
		443282 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		ZN888_HUMAN (46-247): 3.25e-46: 173: 6.86
+	Hs
		535545 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZKSC3_HUMAN (119-321): 6.01e-46: 169: 16.39
+	Hs
		422186 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZKSC8_HUMAN (100-267): 2.5e-42: 160: 9.94