HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: ZKSC1 (P17029)
Zinc finger protein with KRAB and SCAN domains 1 (Zinc finger protein 139) (Zinc finger protein 36) (Zinc finger protein KOX18)
Gene: ZKSCAN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	29568061, 33961781, unassigned1655
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 664 Hs			1 563
+	Hs
		360070 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZFP2_HUMAN (146-512): 2.12e-144: 426: 32.88
+	Hs
		360346 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC3_HUMAN (408-560): 4.62e-68: 231: 51.63
+	Hs
		359633 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZNF3_HUMAN (439-561): 2.34e-60: 208: 52.85
+	Hs
		359594 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC22_HUMAN (426-561): 5.19e-59: 205: 48.53
+	Hs
		360017 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN569_HUMAN (115-343): 4e-46: 174: 8.86
+	Hs
		535320 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZNF19_HUMAN (282-544): 1.76e-95: 300: 42.97
+	Hs
		360385 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN436_HUMAN (237-401): 2.45e-36: 143: 25.44
+	Hs
		67847 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN724_HUMAN (118-317): 3.71e-35: 141: 8.82
+	Hs
		422191 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZN829_HUMAN (251-485): 8.9e-86: 274: 38.56
+	Hs
		360243 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC4_HUMAN (119-346): 3.35e-20: 96.1: 10.00
+	Hs
		535545 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZKSC3_HUMAN (408-560): 4.62e-68: 231: 51.63
+	Hs
		360580 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC21_HUMAN (251-348): 4.65e-13: 73.4: 15.15
+	Hs
		200800 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC12_HUMAN (123-259): 1.09e-12: 72.6: 8.49
+	Hs
		359978 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC8_HUMAN (112-233): 2.42e-10: 65.3: 8.53
+	Hs
		230678 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZN500_HUMAN (426-555): 5.04e-60: 208: 51.54
+	Hs
		485160 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZSC22_HUMAN (426-561): 5.19e-59: 205: 48.53
+	Hs
		535557 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZN436_HUMAN (237-401): 2.45e-36: 143: 25.44
+	Hs
		422285 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZN436_HUMAN (237-401): 2.45e-36: 143: 25.44
+	Hs
		535608 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZKSC5_HUMAN (278-460): 1.04e-32: 135: 30.06
+	Hs
		422186 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZKSC8_HUMAN (112-233): 2.42e-10: 65.3: 8.53