HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 26524528, 29997244, 34079125, 35271311, 19727227, 24623722, 25948554, 29568061, 26264872, 30021884, 33961781, 32344865, 37071682, 21346760, 22412018, 21988832, 11792809, unassigned1913, unassigned1655, 32814053
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, fluorescent resonance energy transfer, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, luminescence based mammalian interactome mapping, two hybrid array, pull down and 3 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament, LTD~LTD
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005638 - lamin filament
GO:0005652 - nuclear lamina
and 9 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 664
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024