HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 22412018
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 3256
+	Hs
		801095 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		KI67_HUMAN (1-3256): 0: 1046: 100.00
+	Hs
		801231 K2C73_HUMAN (23-390): 1.74e-50: 185: 23.85		KI67_HUMAN (1-3256): 0: 1046: 100.00
+	Hs
		359942 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14
+	Hs
		359745 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59
+	Hs
		443385 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59
+	Hs
		360546 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53
+	Hs
		360224 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85
+	Hs
		360045 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83
+	Hs
		595471 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53
+	Hs
		595271 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83
+	Hs
		443883 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53
+	Hs
		443464 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47
+	Hs
		422166 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ANK2_HUMAN (926-3188): 1.69e-11: 73.2: 13.47