HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	24623722
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031647 - regulation of protein stability
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 236
+	Hs
		359727 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		TSN7_HUMAN (1-234): 7.1e-56: 180: 22.31
+	Hs
		360104 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		TSN33_HUMAN (9-233): 7.63e-51: 168: 22.78
+	Hs
		237711 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		TSN2_HUMAN (3-234): 1.88e-44: 150: 39.22
+	Hs
		443434 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		569096 DESM_HUMAN (27-389): 6.1e-28: 119: 30.03		TSN33_HUMAN (9-233): 7.63e-51: 168: 22.78