HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25948554, 32344865
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 164
+	Hs
		359878 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		359909 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34
+	Hs
		359908 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79
+	Hs
		359879 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		SRSF4_HUMAN (11-112): 3.43e-16: 76.6: 39.22