HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: IFFO1 (Q0D2I5)
Non-homologous end joining factor IFFO1 (NHEJ factor IFFO1) (Intermediate filament family orphan 1) (Tumor antigen HOM-TES-103)
Gene: IFFO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.622

The method score is based on:

Property Details
Experiments 24623722, 31548606
Identification Methods two hybrid, anti tag coimmunoprecipitation, pull down
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005882 - intermediate filament
GO:0016363 - nuclear matrix
GO:0035861 - site of double-strand break
GO:1990683 - DNA double-strand break attachment to nuclear envelope
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 664
Hs

1 559
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024