HitPredict

Interactor 1: A0A140VK83 (A0A140VK83)
Protein phosphatase 1, regulatory subunit 7, isoform CRA_b (Testis secretory sperm-binding protein Li 210a)
Gene: PPP1R7

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	LRR_4~LRR_8
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 360 Hs			1 2527
+	Hs
		2885 A0A0G2JPP5_HUMAN (110-360): 6.41e-32: 129: 19.38		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	At
		99021 RGI4_ARATH (20-222): 1.13e-27: 116: 15.96		FLS2_ARATH (804-1465): 3.45e-151: 505: 16.05
+	At
		221535 Y2317_ARATH (12-266): 1.79e-29: 121: 15.81		BAME3_ARATH (794-1595): 1.95e-150: 497: 14.30
+	At
		99006 RGI4_ARATH (20-222): 1.13e-27: 116: 15.96		BAME3_ARATH (794-1595): 1.95e-150: 497: 14.30
+	At
		1114702 TDR_ARATH (10-224): 2.73e-21: 97.6: 12.61		ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41
+	At
		249741 Y1723_ARATH (12-230): 1.15e-26: 113: 16.02		BAME3_ARATH (794-1595): 1.95e-150: 497: 14.30
+	At
		249746 BRL2_ARATH (13-231): 9.02e-19: 89.9: 13.14		BAME3_ARATH (794-1595): 1.95e-150: 497: 14.30
+	At
		84509 BRL2_ARATH (13-231): 9.02e-19: 89.9: 13.14		GSO1_ARATH (841-1595): 1.93e-123: 425: 14.72
+	Zm
		42762 A0A1D6P6J2_MAIZE (167-359): 1.13e-26: 112: 24.75		K7V4X2_MAIZE (795-1429): 1.29e-103: 363: 14.69
+	At
		83985 Y1723_ARATH (12-230): 1.15e-26: 113: 16.02		Y1743_ARATH (883-1624): 7.49e-103: 360: 14.17
+	At
		99002 RGI4_ARATH (20-222): 1.13e-27: 116: 15.96		RGI4_ARATH (1221-2146): 2.44e-86: 310: 14.84
+	Gm
		1341216 CLV1B_SOYBN (12-266): 9.88e-26: 110: 14.39		CLV1B_SOYBN (1858-2134): 8.56e-82: 294: 23.61
+	At
		99004 RGI4_ARATH (20-222): 1.13e-27: 116: 15.96		BAME1_ARATH (1119-1672): 2.48e-71: 263: 13.35
+	At
		85103 RGI2_ARATH (19-251): 3.3e-28: 118: 18.70		ERL2_ARATH (1183-1706): 5.31e-63: 237: 12.75
+	At
		99012 RGI4_ARATH (20-222): 1.13e-27: 116: 15.96		ERL2_ARATH (1183-1706): 5.31e-63: 237: 12.75
+	Zm
		19443 A0A1D6HD42_MAIZE (7-178): 6.42e-22: 99.5: 12.22		A0A1D6HD42_MAIZE (1850-2138): 2.54e-60: 230: 20.12
+	At
		1323498 TDR_ARATH (10-224): 2.73e-21: 97.6: 12.61		BRL3_ARATH (780-1151): 1.32e-42: 174: 12.21
+	At
		1338065 BRL2_ARATH (13-231): 9.02e-19: 89.9: 13.14		RGI1_ARATH (1391-1847): 7.61e-21: 102: 13.77
+	At
		1352203 Y1723_ARATH (12-230): 1.15e-26: 113: 16.02		BRL2_ARATH (1470-1771): 1.68e-09: 65.8: 10.33
+	At
		1338953 BRL2_ARATH (13-231): 9.02e-19: 89.9: 13.14		Y1571_ARATH (1498-1748): 1.08e-13: 79.3: 13.62