Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: LBR (Q14739)
Delta(14)-sterol reductase LBR (Delta-14-SR) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (C14SR) (Integral nuclear envelope inner membrane protein) (LMN2R) (Lamin-B receptor) (Sterol C14-reductase)
Gene: LBR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.722

The method score is based on:

Property Details
Experiments 25948554, 29568061, 34079125, 32344865, 22412018, unassigned1655
Identification Methods affinity chromatography technology, proximity labelling technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0031965 - nuclear membrane
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 664
Hs

1 615
+ Mm
+ Hs
+ Dr
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024