Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: TOIP1 (Q5JTV8)
Torsin-1A-interacting protein 1 (Lamin-associated protein 1B) (LAP1B)
Gene: TOR1AIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.738

The method score is based on:

Property Details
Experiments 16248985, 24623722, 29568061, 34079125, 8324822, 32344865, 22412018
Identification Methods two hybrid, proximity labelling technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0031965 - nuclear membrane
GO:0034504 - protein localization to nucleus
GO:0090435 - protein localization to nuclear envelope
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 664
Hs

1 583
+ Mm
+ Hs
+ Dr

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024