HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: RIF1 (Q5UIP0)
Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog)
Gene: RIF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32344865, 22412018
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031965 - nuclear membrane GO:0035861 - site of double-strand break
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 2472
+	Hs
		443575 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		RIF1_HUMAN (1-2472): 0: 1703: 100.00
+	Hs
		360045 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		NIPBL_HUMAN (948-1837): 3.15e-19: 98.1: 12.40
+	Hs
		359745 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		MAP1B_HUMAN (745-2457): 3e-18: 94.6: 8.05
+	Hs
		359942 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		MDC1_HUMAN (958-2272): 4.95e-18: 93.9: 10.74
+	Hs
		360224 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		TITIN_HUMAN (1353-2455): 9.33e-09: 63.8: 8.91
+	Hs
		595271 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		NIPBL_HUMAN (948-1837): 3.15e-19: 98.1: 12.40
+	Hs
		443620 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		CNTRL_HUMAN (924-2161): 4.76e-36: 153: 10.94
+	Hs
		422135 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		MTAP2_HUMAN (941-2318): 1.02e-23: 112: 9.86
+	Hs
		443385 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		MAP1B_HUMAN (745-2457): 3e-18: 94.6: 8.05
+	Hs
		443464 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		ANK2_HUMAN (1320-2406): 6.35e-18: 93.7: 9.80
+	Hs
		422166 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ANK2_HUMAN (1320-2406): 6.35e-18: 93.7: 9.80