HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: TEX14 (Q8IWB6)
Inactive serine/threonine-protein kinase TEX14 (Protein kinase-like protein SgK307) (Sugen kinase 307) (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein)
Gene: TEX14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 664 Hs			1 1497
+	Mm
		403456 K2C5_MOUSE (23-401): 7.65e-117: 363: 24.61		SRC_MOUSE (109-527): 5.17e-108: 355: 16.96
+	Hs
		359557 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		NTRK1_HUMAN (1-518): 1.81e-123: 407: 15.60
+	Hs
		280771 KRT36_HUMAN (31-457): 9.65e-119: 364: 23.83		HCK_HUMAN (238-529): 9.35e-83: 283: 20.81
+	Hs
		359915 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ILK_HUMAN (27-513): 1.67e-113: 367: 17.47
+	Hs
		384683 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		NTRK1_HUMAN (1-518): 1.81e-123: 407: 15.60
+	Hs
		384248 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		NTRK1_HUMAN (1-518): 1.81e-123: 407: 15.60
+	Hs
		1033501 K2C73_HUMAN (23-390): 1.74e-50: 185: 23.85		ILK_HUMAN (27-513): 1.67e-113: 367: 17.47
+	Hs
		595211 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		ILK_HUMAN (27-513): 1.67e-113: 367: 17.47
+	Hs
		359584 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		HCK_HUMAN (238-529): 9.35e-83: 283: 20.81
+	Hs
		443382 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		ABL2_HUMAN (110-1098): 1.99e-123: 417: 12.87
+	Hs
		384129 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		NTRK1_HUMAN (1-518): 1.81e-123: 407: 15.60
+	Hs
		443403 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		BLK_HUMAN (44-525): 6.52e-118: 381: 15.22
+	Hs
		433235 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		YES_HUMAN (239-527): 5.22e-109: 358: 20.55
+	Hs
		411976 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		FYN_HUMAN (222-527): 1.72e-108: 357: 20.07
+	Hs
		433246 DESM_HUMAN (27-389): 6.1e-28: 119: 30.03		YES_HUMAN (239-527): 5.22e-109: 358: 20.55
+	Hs
		442865 KRT35_HUMAN (30-387): 1.7e-41: 158: 24.58		HCK_HUMAN (238-529): 9.35e-83: 283: 20.81
+	Hs
		337855 K2C5_HUMAN (24-390): 2.24e-117: 364: 25.95		EGFR_HUMAN (270-483): 6.22e-10: 66.2: 23.04
+	Hs
		337731 K2C6A_HUMAN (23-407): 5.26e-116: 360: 23.71		EGFR_HUMAN (270-483): 6.22e-10: 66.2: 23.04
+	Hs
		337732 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		EGFR_HUMAN (270-483): 6.22e-10: 66.2: 23.04
+	Hs
		337806 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		EGFR_HUMAN (270-483): 6.22e-10: 66.2: 23.04