HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: PPIL4 (Q8WUA2)
Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4)
Gene: PPIL4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 492
+	Hs
		595328 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		PPIL4_HUMAN (1-492): 1.42e-105: 325: 100.00
+	Hs
		360405 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		PPIL3_HUMAN (1-166): 6.49e-65: 209: 41.32
+	Hs
		360570 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		PPIL1_HUMAN (2-161): 2.44e-63: 205: 36.88
+	Mm
		821737 LMNA_MOUSE (1-664): 1.23e-70: 243: 94.90		PPIL1_MOUSE (2-161): 2.19e-63: 205: 36.88
+	Hs
		360061 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		CWC27_HUMAN (3-168): 6.14e-26: 112: 41.32
+	Hs
		595277 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		CWC27_HUMAN (3-168): 6.14e-26: 112: 41.32