HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: ZKSC4 (Q969J2)
Zinc finger protein with KRAB and SCAN domains 4 (P373c6.1) (Zinc finger protein 307) (Zinc finger protein 427)
Gene: ZKSCAN4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 664 Hs			1 545
+	Hs
		360070 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZFP2_HUMAN (134-482): 1.26e-102: 318: 28.65
+	Hs
		360385 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN436_HUMAN (285-456): 3.4e-81: 263: 51.16
+	Hs
		359633 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZNF3_HUMAN (167-403): 5.41e-69: 230: 29.96
+	Hs
		422191 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZN829_HUMAN (180-539): 9.85e-125: 374: 36.84
+	Hs
		200800 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC12_HUMAN (86-347): 6.15e-63: 218: 13.75
+	Hs
		360017 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN569_HUMAN (403-544): 6.81e-60: 212: 40.56
+	Hs
		360346 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC3_HUMAN (121-373): 1.19e-52: 189: 17.25
+	Hs
		360580 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC21_HUMAN (428-544): 1.37e-46: 171: 34.75
+	Hs
		535557 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZN436_HUMAN (285-456): 3.4e-81: 263: 51.16
+	Hs
		422285 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZN436_HUMAN (285-456): 3.4e-81: 263: 51.16
+	Hs
		67847 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN724_HUMAN (41-236): 1.61e-23: 106: 6.73
+	Hs
		359594 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC22_HUMAN (130-287): 1.27e-19: 93.8: 7.88
+	Hs
		359631 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC1_HUMAN (120-267): 4.16e-15: 80: 6.67
+	Hs
		359978 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC8_HUMAN (510-544): 4.67e-09: 61: 45.71
+	Hs
		535545 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZKSC3_HUMAN (121-373): 1.19e-52: 189: 17.25
+	Hs
		535608 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZKSC5_HUMAN (169-426): 3.28e-49: 183: 21.98
+	Hs
		230678 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZN500_HUMAN (142-372): 1.17e-38: 149: 21.37
+	Hs
		535603 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZN232_HUMAN (466-543): 3.52e-22: 101: 37.18
+	Hs
		485160 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZSC22_HUMAN (130-287): 1.27e-19: 93.8: 7.88
+	Hs
		422186 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZKSC8_HUMAN (510-544): 4.67e-09: 61: 45.71