HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: DNJC1 (Q96KC8)
DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1)
Gene: DNAJC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33957083, 22412018
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031965 - nuclear membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 554
+	Hs
		975713 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		DNJC1_HUMAN (1-554): 8.06e-118: 361: 100.00
+	Hs
		595361 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		DNJC1_HUMAN (1-554): 8.06e-118: 361: 100.00
+	Hs
		360514 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		SEC63_HUMAN (13-552): 6.24e-69: 238: 16.03
+	Dr
		48759 B3DKC5_DANRE (9-597): 8e-53: 194: 65.08		A0JMB9_DANRE (26-554): 2e-91: 292: 60.19
+	Hs
		360483 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		DJB12_HUMAN (44-287): 5.13e-46: 167: 18.11
+	Hs
		975754 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		SEC63_HUMAN (13-552): 6.24e-69: 238: 16.03
+	Hs
		595460 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		SEC63_HUMAN (13-552): 6.24e-69: 238: 16.03
+	Hs
		360402 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		DJC25_HUMAN (54-319): 1.29e-39: 149: 17.25
+	Hs
		975759 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		DJC16_HUMAN (55-230): 1.64e-39: 155: 23.46
+	Hs
		595098 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		DNJB1_HUMAN (62-316): 5.43e-42: 155: 14.55
+	Hs
		595475 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		DJC16_HUMAN (55-230): 1.64e-39: 155: 23.46
+	Hs
		975730 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		DJC25_HUMAN (54-319): 1.29e-39: 149: 17.25
+	Hs
		360128 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		DJC10_HUMAN (65-135): 5.65e-12: 70.5: 48.61
+	Hs
		595404 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		DJC25_HUMAN (54-319): 1.29e-39: 149: 17.25
+	Hs
		535519 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		DNJA3_HUMAN (13-217): 1.05e-41: 158: 21.43
+	Hs
		257987 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		DNJB6_HUMAN (64-126): 1.3e-11: 67.8: 52.31
+	Hs
		257911 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		DNJB6_HUMAN (64-126): 1.3e-11: 67.8: 52.31