HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: H2B1L (Q99880)
Histone H2B type 1-L (Histone H2B.c) (H2B/c)
Gene: H2BC13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 126
+	Hs
		359990 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		H2B2E_HUMAN (1-126): 2.16e-54: 168: 97.62
+	Hs
		241411 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		H2B1K_HUMAN (1-126): 4.5e-54: 167: 97.62
+	Hs
		359572 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		H2B1J_HUMAN (1-126): 2.66e-54: 167: 96.83
+	Hs
		359831 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		H2B1C_HUMAN (1-126): 4.4e-54: 167: 98.41
+	Hs
		359699 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		H2B1B_HUMAN (1-126): 5.99e-54: 166: 96.03
+	Hs
		359809 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		H2B1D_HUMAN (1-126): 1.27e-53: 166: 97.62
+	Hs
		595248 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		H2B2E_HUMAN (1-126): 2.16e-54: 168: 97.62
+	Hs
		443362 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		H2B1B_HUMAN (1-126): 5.99e-54: 166: 96.03