HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: ZKSC3 (Q9BRR0)
Zinc finger protein with KRAB and SCAN domains 3 (Zinc finger and SCAN domain-containing protein 13) (Zinc finger protein 306) (Zinc finger protein 309) (Zinc finger protein 47 homolog) (Zf47) (Zfp-47)
Gene: ZKSCAN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29568061
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 664 Hs			1 538
+	Hs
		359633 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZNF3_HUMAN (167-535): 5.93e-153: 446: 39.76
+	Hs
		360385 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN436_HUMAN (255-531): 8.67e-128: 383: 44.09
+	Hs
		200800 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC12_HUMAN (12-452): 2.19e-119: 366: 25.84
+	Hs
		359594 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC22_HUMAN (335-537): 1.29e-100: 314: 45.85
+	Hs
		359631 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC1_HUMAN (376-537): 1.26e-77: 256: 46.95
+	Hs
		535557 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZN436_HUMAN (255-531): 8.67e-128: 383: 44.09
+	Hs
		422285 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZN436_HUMAN (255-531): 8.67e-128: 383: 44.09
+	Hs
		422191 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZN829_HUMAN (252-532): 2.72e-126: 378: 44.88
+	Hs
		360580 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZSC21_HUMAN (394-537): 8.32e-63: 214: 43.84
+	Hs
		485160 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZSC22_HUMAN (335-537): 1.29e-100: 314: 45.85
+	Hs
		360017 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN569_HUMAN (100-282): 1.37e-37: 149: 11.41
+	Hs
		360243 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC4_HUMAN (437-537): 6.28e-37: 145: 32.04
+	Hs
		359978 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZKSC8_HUMAN (100-226): 6.79e-27: 116: 10.94
+	Hs
		360070 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZFP2_HUMAN (358-533): 2.75e-26: 113: 37.78
+	Hs
		67847 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN724_HUMAN (98-227): 4.17e-23: 105: 9.92
+	Hs
		535608 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZKSC5_HUMAN (246-479): 1.19e-66: 232: 29.80
+	Hs
		422186 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZKSC8_HUMAN (100-226): 6.79e-27: 116: 10.94
+	Hs
		535545 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZKSC3_HUMAN (467-537): 1.77e-23: 106: 43.66
+	Hs
		230678 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZN500_HUMAN (473-536): 1.64e-23: 105: 40.63
+	Hs
		443282 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		ZN888_HUMAN (93-192): 5.59e-11: 67.2: 8.00