HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: UN45A (Q9H3U1)
Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1)
Gene: UNC45A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	24623722
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007517 - muscle organ development GO:0016607 - nuclear speck GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 944
+	Hs
		213437 K2C6A_HUMAN (23-407): 5.26e-116: 360: 23.71		SGTA_HUMAN (1-141): 4.45e-39: 149: 27.66
+	Hs
		360542 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		CHIP_HUMAN (8-159): 1.54e-35: 139: 29.30
+	Hs
		174529 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		OGT1_HUMAN (3-192): 2.53e-24: 112: 12.63
+	Hs
		359697 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		STIP1_HUMAN (4-228): 9.18e-17: 86.8: 15.32
+	Dr
		71527 B3DKC5_DANRE (9-597): 8e-53: 194: 65.08		Q6ZM24_DANRE (7-138): 2.47e-32: 129: 30.30
+	Hs
		443415 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		PPP5_HUMAN (10-180): 3.77e-39: 154: 23.98
+	Hs
		684648 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		STIP1_HUMAN (4-228): 9.18e-17: 86.8: 15.32
+	Hs
		595112 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		STIP1_HUMAN (4-228): 9.18e-17: 86.8: 15.32
+	Hs
		443879 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		CHIP_HUMAN (8-159): 1.54e-35: 139: 29.30
+	Hs
		174563 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		OGT1_HUMAN (3-192): 2.53e-24: 112: 12.63
+	Hs
		443358 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		STIP1_HUMAN (4-228): 9.18e-17: 86.8: 15.32
+	Hs
		569089 DESM_HUMAN (27-389): 6.1e-28: 119: 30.03		LONF3_HUMAN (16-126): 3.42e-10: 65.9: 36.04