HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 779
+	Hs
		975735 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		595415 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		443807 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		531603 K2C5_HUMAN (24-390): 2.24e-117: 364: 25.95		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		360044 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		360147 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		595270 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		595261 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		443693 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		CNKR2_HUMAN (1-468): 1.39e-46: 181: 13.77
+	Hs
		595304 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Mm
		440274 NFL_MOUSE (28-411): 3.76e-26: 115: 29.64		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Hs
		443818 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		1121886 Q53SB5_HUMAN (27-389): 6.1e-28: 119: 30.03		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		569125 DESM_HUMAN (27-389): 6.1e-28: 119: 30.03		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		443650 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		422231 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		443800 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		TARA_HUMAN (49-471): 7.83e-20: 97.3: 15.21